"Don't Let Go (Love)" is a song by American R&B group En Vogue. It was written by Ivan Matias, Andrea Martin, Marqueze Etheridge and produced by Organized Noize and Ivan Matias for the Set It Off soundtrack (1996), also appearing on the group's third album, EV3 (1997). The song was the band's last single to feature former band member Dawn Robinson, on lead vocals, and became En Vogue's biggest international single, peaking in the top ten of many countries. According to Billboard magazine, the single ranked as the #83rd most successful single of the 1990s.

The worldwide popularity of this song compelled Elektra mogul Sylvia Rhone to place En Vogue back in the studio to record their album EV3 for release in 1997. However, Dawn Robinson felt a solo career was not feasible while she was still a member of En Vogue, while the other group members plus the record producers and label executives were focused on the new En Vogue album. Forced to choose, Robinson decided to leave En Vogue for a solo career with Dr. Dre's Aftermath Records. The turn of events following the success of "Don't Let Go (Love)" was the beginning of a long and tumultuous era for En Vogue as member changes became quite frequent.

"Don't Let Go (Love)" became the third En Vogue track to peak at #2 on the U.S. Billboard Hot 100 where it was the group's fifth and final Top Ten hit. The song was a #1 R&B song for 1 week becoming En Vogue's sixth and final #1 R&B Hit to date. It hit #5 in the UK in early 1997 and spent 13 weeks in the UK top 40, eight of those weeks in the top ten. The single re-entered the UK chart at number 23 in 2011 after girl group Little Mix performed the song on the eighth series of British television talent contest The X Factor on November 19, 2011: the En Vogue track reached #23 on the UK chart and also returned to the Irish charts at #50.

The single sold 1.3 million copies in the United States and was certified platinum by the RIAA. In October 2011, NME placed it at number 127 on its list "150 Best Tracks of the Past 15 Years". The song was notable in the 1996 movie Set It Off.

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