"Don't Give Up" is a song by Christian rock band Sanctus Real from their 2006 album The Face of Love. The song was released as a radio single in early 2007, and reached number 1 on R&R's Christian CHR chart in the beginning of May 2007. It is the band's fifth number 1 hit, and the second chart-topping single from The Face of Love. It ended 2007 as the 6th most played song of the year on Christian contemporary hit radio.

"Don't Give Up" is a rock-based song which encourages the longevity of marriage relationships. Lead singer Matt Hammit said: "The song was inspired by close friends of ours that made difficult decisions to end their marriages. I'm not here to judge those decisions, but as a band we want to be a voice for lasting love and commitment in a world where breaking vows is as common as taking them."

The song has been compared to U2's "Beautiful Day" and Coldplay's "Speed of Sound", having similarities in style to the band's previous album, Fight the Tide.

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