Dominic Constantine, Prince of Löwenstein-Wertheim-Rochefort (16 May 1762 – 18 April 1814) was the fourth and last reigning Prince of the Rochefort line of the House of Löwenstein-Wertheim.

He was born in Nancy as the third children and first son of Prince Theodor Alexander of Löwenstein-Wertheim-Rochefort (1722 - 1780), seventh and youngest son of Dominic Marquard, 3rd Prince of Löwenstein-Wertheim-Rochefort (1690 - 1735), and his wife Countess Luise of Leiningen-Dachsburg-Hartenburg (1735 - 1805) a granddaughter of Johann Friedrich, Count of Leiningen-Hartenburg (1661-1722). Throughout his parents were born six children, but only two reached adulthood.

He was baptized on the same day of his birth in the parish church of San Rocco in Nancy. He grew up in Strasbourg, where he also attended the military school. In Fulda he began a serious course of study under the supervision of a tutor, and since it was foreseeable that he would be the successor to his uncle Charles Thomas, he settled in Wertheim in 1783.

On 5 May 1780 he married in Nancy Princess Leopoldine of Hohenlohe-Bartenstein, by whom he had seven children:

After the death of his first wife he married Countess Maria Kreszentia of Königsegg-Rothenfels and had three more children:

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