Domenico and Francesco Pizzigano, known as the Pizzigani brothers, were 14th-century Venetian cartographers. Their surname is sometimes given as Pizigano (only one 'z') in older sources.
Pizzigani brothers are principally known for the construction of a portolan chart, signed and dated 1367, currently held by the Biblioteca Palatina of Parma (Ms.Parm.1612). Measuring 138 by 92 cm, it is one of the largest maps of that era.
There is some controversy over the authorship. The note on the edge of the map, states (in one reading): ""MCCCLXVII. Hoc opus compoxuid franciscus pizigano veneciar et domnus pizigano In Venexia meffecit marcus die XII decembris.". The common assumption is that this refers to two brothers, Francesco Pizzigano and Domenico Pizzigano. Among the various alternative hypothesis is that Francesco was the son of Domenico, rather than his brother (and that Domenico might be dead by this date); that 'domnus' is a title for a priest, that the proper first name of the second author is Marco, that a close reading of the authorship note seems more like 'rardus' – or (Ge)rardus, Gerardo; that there might be three brothers (Francesco, Domenico, Marco/Gerardo), etc. It was customary to refer to the brothers as the Pizigani (one z), until the discovery of the 1424 map of Zuane Pizzigano in the 20th century suggested a re-spelling to a double z.
The Pizzigani portolan of 1367 is notable for going beyond the normal geographical boundaries of contemporary maps (Mediterranean and Black Seas) to include large swathes of the Atlantic Ocean, the northerly Scandinavian peninsula and the Baltic and Caspian Seas.
The 1367 Pizzigani chart gives an expanded depiction of the Canary Islands, showing eight of them, reflecting the knowledge accumulated since the 1339 Angelino Dulcert chart. It also includes the fantasy islands of Brasil (in the open ocean, with ships and dragons of Arab legend depicted around it). North of the real Canaries, the Pizzigani brothers also depicted a fictional cluster of Fortunate Islands, intended to capture Saint Brendan's Island, graced by an image of Brendan himself in monastic garb. The Pizzigani map is also the first in which the mythical Isle of Mam (southwest of Ireland) makes its first appearance.