Domenico Piola (1627 – 8 April 1703) was a Genoese painter of the Baroque period. He was the leading artist in Genoa in the second half of the 17th century, working on ceiling frescoes for many Genoese churches and palaces and canvas paintings for private collectors. His family studio was highly prolific. He was a frequent collaborator with other artists.
Piola was an Italian painter, draughtsman, printmaker and designer. He was the leading artist in Genoa in the second half of the 17th century, working for both public and private collectors. His first teacher was his 17-year older brother-in-law Stefano Camogli. Piola was further trained by his older brother Pellegro and then studied under Pellegro’s teacher, Giovanni Domenico Cappellino (1580–1651).
From 1650 onwards, the Piola family played a dominant role in the decoration of Genoese ceilings for nearly a century. While Domenico was the key figure in the family studio, known as Casa Piola, in the second half of the 17th century, other members were Piola's younger brother, his brother-in-law Stefano Camogli, his three sons, and his two sons-in-law. The studio streamlined the design and production of decorated ceilings. The studio also produced designs for sculptors and for craftsmen in wood, ceramics and metalwork.
In 1684–5 Domenico visited Milan, Piacenza, Bologna and Asti. At Piacenza, he painted decorations in the Casa Baldini. In Genoa in 1688 he and Gregorio de’ Ferrari began to decorate rooms in the Palazzo Rosso on the theme of the four seasons, Piola executing Autumn and Winter and Ferrari the more lyrical Spring and Summer. Preparatory drawings for Winter survive (Genoa, Palazzo Rosso; London, British Museum).