The soundtrack for series 6 of Doctor Who was released on December 19, 2011. It is the third 2-CD release that Silva Screen has produced for the new series. The album was initially due for release on December 5, 2011, but was later delayed until December 19, 2011. Also, on November 1, 2011, Murray Gold and Jake Jackson both posted on their Twitter accounts that they're allowing viewers the chance to suggest different musical pieces from the episodes of series 6 that may have been included on the soundtrack. On November 24, Silva Screen announced the full track list of the series 6 soundtrack.

For the sixth series of Doctor Who, composer Murray Gold and conductor Ben Foster continued to write variations and rearrangements of themes introduced in the previous season. The Eleventh Doctor's themes, "I Am The Doctor" and "The Mad Man With A Box", were Americanized for the series opener, "The Impossible Astronaut" / "Day of the Moon", along with the Pandorica motif ("I Am The Doctor In Utah", "1969", "The Impossible Astronaut", "Help Is On Its Way", "Day of the Moon", "The Majestic Tale (Of A Madman In A Box)"). The track "Day of the Moon" was the intended score during the massacre of the Silence. It was replaced at the last minute by "The Majestic Tale (of a Mad Man in a Box)." For "The Curse of the Black Spot", Gold wrote mostly derived themes from pirate folklore, while Halia Meguid performed the Siren’s song, "Deadly Siren".

"The God Complex" had a mostly electronic score. The "Tick Tock, Round the Clock" melody from Night Terrors was incorporated into later scripts such as "Closing Time" and "The Wedding of River Song" by Steven Moffat. Non-UK broadcasts of Series 6 included the short track "Locked On" during a brief pre-titles recap by Karen Gillan. For "The Impossible Astronaut" / "Day of the Moon", "A Good Man Goes to War" / "Let's Kill Hitler", and "The Wedding of River Song", Gold wrote variations of River Song’s theme, "A River of Tears" ("Melody Pond", "Forgiven", "The Wedding of River Song"), while expanding on Amy Pond's themes ("Little Amy", "Amy in the TARDIS" "Amy's Theme") in "The Rebel Flesh" / "The Almost People" and "The Girl Who Waited". Gold also sampled older compositions such as "All the Strange, Strange Creatures" and "The Doctor’s Theme".

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