Diathesis–stress model

The diathesis–stress model is a psychological theory that attempts to explain behavior as a predispositional vulnerability together with stress from life experiences. The term diathesis derives from the Greek term (διάθεσις) for disposition, or vulnerability, and it can take the form of genetic, psychological, biological, or situational factors. A large range of individual differences exist between persons in their vulnerability to the development of disorder.

The diathesis, or predisposition, interacts with the subsequent stress response of an individual. Stress refers to a life event or series of events that disrupt a person's psychological equilibrium and potentially serves as a catalyst to the development of a disorder. Thus, the diathesis–stress model serves to explore how biological or genetic traits (diatheses) interact with environmental influences (stressors) to produce disorders, such as depression, anxiety, or schizophrenia.

The diathesis–stress model asserts that if the combination of the predisposition and the stress exceeds a threshold, the person will develop a disorder.

The use of term diathesis in the fields of medicine and psychiatry dates back to the 1800s; however, the diathesis–stress model was not introduced and utilized to describe the development of psychopathology until it was used to explain schizophrenia in the 1960s. The diathesis–stress model is used in many fields of psychology, specifically for studying the development of psychopathology. It is useful for the purposes of understanding the interplay of nature and nurture in the susceptibility to psychological disorders throughout the lifespan. Diathesis–stress models can also assist in determining who will develop a disorder and who will not. For example, in the context of depression, the diathesis–stress model can help explain why Person A may become depressed while Person B does not, even when exposed to the same stressors. More recently, the diathesis–stress model has been used to explain why some individuals are more at risk for developing a disorder than others. For example, children who have a family history of depression are generally more vulnerable to developing a depressive disorder themselves. A child who has a family history of depression and who has been exposed to a particular stressor, such as exclusion or rejection by his or her peers, would be more likely to develop depression than a child with a family history of depression that has an otherwise positive social network of peers.

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