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Dextran 70

Dextran 70
Clinical data
Trade names RescueFlow, others
AHFS/Drugs.com Monograph
Pregnancy
category
  • US: C (Risk not ruled out)
Routes of
administration
intravenous
ATC code
Legal status
Legal status
Identifiers
CAS Number
DrugBank
Chemical and physical data
Molar mass 70,000 kDa

Dextran 70 is a type of fluid given by injection into a vein to expand blood volume. Specifically it is used for shock such as that caused by bleeding or burns when blood transfusions are not quickly available. However, it does not carry oxygen.

Common side effects include vomiting, fever, and joint pains. Other side effects include allergic reactions and poor blood clotting. It is not recommended in people with kidney failure, significant heart failure, or a clotting disorder. Use is also not recommended during pregnancy. It works by pulling fluid from the extravascular space into the blood vessels.

Dextran 70 was approved for medical use in 1947. It is on the World Health Organization's List of Essential Medicines, the most effective and safe medicines needed in a health system. The wholesale cost in the developing world is about 4.10 to 5.25 USD per 500 ml. In the United Kingdom this dose costs the NHS about 57.00 pounds. In the United States it costs about 25 to 50 USD per dose. It comes in either sodium chloride solution or glucose solution.


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