Coordinates: 42°14′45″N 83°36′33″W / 42.245961°N 83.609143°W
Depot Town is a commercial area, with some residences above storefronts, in Ypsilanti, Michigan's historic district. Depot Town proper consists of East Cross Street from the Huron River to North River Street, and a small area on the 300-block of North River Street. However, several blocks in the surrounding area are also commonly referred to as part of Depot Town. These areas include Riverside Park, Frog Island Park (both of which are on the Huron River), and River Street extending north and south for several blocks. First established in the late 1830s, most of the buildings standing today were constructed between 1850 and 1880. Over the years, Depot Town has included hotels, an Underground Railroad station, an American Civil War barracks, and a building that has housed a bar and restaurant continuously for more than 150 years, switching to soft drinks during Prohibition. Today the area is dominated by restaurants and stores. Depot Town also hosts several large summer festivals each year, as well as weekly bike nights and cruise nights.
Depot Town was created after the Ypsilanti Train Depot was opened in 1838. As the railroad connected Ypsilanti, MI with Detroit, the area surrounding the depot grew. The commercial community known as Depot Town was built over the thirty years following the arrival of the railroad, and most of the buildings standing today were built from 1850 to 1880. In the early years, Depot Town included a flour mill, a large farmers' store, an iron foundry, a fire department, a clothing store, and paved streets. Ypsilanti's original city hall and jail were built just across the Huron River from Depot Town on West Cross Street. As the depot was built one mile north of the Chicago Road (now Michigan Avenue), the community of Ypsilanti was split between competing locations.