Deltapapillomavirus | |
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Virus classification | |
Group: | Group I (dsDNA) |
Family: | Papillomaviridae |
Genus: | Deltapapillomavirus |
Type Species | |
Deltapapillomavirus is a genus of viruses, in the family Papillomaviridae. Ruminants serve as natural hosts. There are currently six species in this genus including the type species Deltapapillomavirus 1. Diseases associated with this genus include: warts (papillomas and fibropapillomas) of the skin and alimentary tract (rarely cancers of the alimentary tract and urinary bladder); possibly responsible for the skin tumour equine sarcoid in horses and donkeys.
Group: dsDNA
Viruses in Deltapapillomavirus are non-enveloped, with icosahedral geometries. The diameter is around 60 nm. Genomes are circular, around 8kb in length.
Viral replication is nuclear. Entry into the host cell is achieved by attachment of the viral proteins to host receptors, which mediates endocytosis. Replication follows the dsDNA bidirectional replication model. Dna templated transcription, with some alternative splicing mechanism is the method of transcription. The virus exits the host cell by nuclear envelope breakdown. Ruminants serve as the natural host. Transmission routes are contact.