Deianira, Deïanira, or Deianeira (/ˌdeɪ.əˈnaɪərə/;Greek: Δηϊάνειρα, Dēiáneira, or Δῃάνειρα, Dēáneira, [dɛːiáneːra]), also known as Dejanira, is a figure in Greek mythology whose name translates as "man-destroyer" or "destroyer of her husband". The name Deianira refers to two separate characters in Greek mythology.
The better-known Deianira was a wife of Heracles and, in late Classical accounts, his unwitting murderer, killing him with the poisoned Shirt of Nessus. She is the main character in Sophocles' play Women of Trachis. The less well-known Deianira was an Amazon, killed by Heracles during his quest for the girdle of Hippolyta.
Deianira was the daughter of Althaea and her husband Oeneus (whose name means "wine-man"), the king of Calydon (after the wine-god gave the king the vine to cultivate), and the half-sister of Meleager. She also was said to have become the mother of Macaria (who saved the Athenians from defeat by Eurystheus).