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De Humani Corporis Fabrica

De humani corporis fabrica
Vesalius Fabrica fronticepiece.jpg
Title page. The full title is Andreae Vesalii Bruxellensis, scholae medicorum Patauinae professoris, de Humani corporis fabrica Libri septem (Andreas Vesalius of Brussels, professor at the school of medicine at Padua, on the fabric of the Human body in seven Books).
Author Andreas Vesalius
Illustrator 'Studio of Titian'
Country Italy
Subject Anatomy
Genre Illustrated textbook
Publisher School of medicine, Padua
Publication date
1543

De humani corporis fabrica libri septem (Latin for "On the fabric of the human body in seven books") is a set of books on human anatomy written by Andreas Vesalius (1514–1564) and published in 1543. It represented a major advance in the history of anatomy.

The collection of books is based on his Paduan lectures, during which he deviated from common practice by dissecting a corpse to illustrate what he was discussing. Dissections had previously been performed by a barber surgeon under the direction of a doctor of medicine, who was not expected to perform manual labour. Vesalius's magnum opus presents a careful examination of the organs and the complete structure of the human body. This would not have been possible without the many advances that had been made during the Renaissance, including artistic developments in literal visual representation and the technical development of printing with refined woodcut engravings. Because of these developments and his careful, immediate involvement, Vesalius was able to produce illustrations superior to any produced previously.

Vesalius arranged his work into seven books.

The first book constitutes about a quarter of the entire collection. It presents Vesalius' observations on human bones and cartilage, which he collected from cemeteries. It covers the physical appearance of human bones and the differentiation of human bones and cartilage by function. In each chapter Vesalius describes the bones in great detail, explaining their physical qualities in different ways. In the opening chapters, Vesalius "gives general aspects of bones and skeletal organisation, dealing with the differences in texture, strength, and resilience between bone and cartilage; explaining the complex differences between types of joints and reviewing some basic elements of descriptive techniques and terminology." A major theme of this book is whether Galen described the bones of the human skeleton accurately. When Vesalius lectured on the human skeleton, he also had to present the bones of animals to give credibility to Galen's observations.

Here Vesalius describes the structure of the muscles, the agents used in creating movement by the body, and the material used to hold the joints together. Through his observations of butchers cutting meat, he was able to incorporate the skills they used in the dissection of the human body. The order in which to dissect a human body to effectively observe each muscle in the body is laid out. Each illustration displays a deepening view of the human body which can be followed while dissecting a human body. Vesalius also mentions the instruments needed to perform a dissection. Here Vesalius begins to describe how Galen's anatomical descriptions do not match his own observations. In order to show respect to Galen, he suggests Galen's use of anatomical structure is in fact correct, but not for humans. He even continues to describe some of the structures in the way Galen would.


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