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David H. Koch Institute for Integrative Cancer Research

Koch Institute for Integrative Cancer Research at MIT
Logo of the David H. Koch Institute
Established October 9, 2007
Research type Basic (non-clinical) research
Budget $24.5 million
Field of research
Cancer research
Director Tyler Jacks
Faculty 25
Staff 500
Address 77 Massachusetts Ave.
Building 76
Location Cambridge, Massachusetts
Campus 180,000 square feet (17,000 m2)
Affiliations National Cancer Institute
Operating agency
Massachusetts Institute of Technology
Website web.mit.edu/ki

The Koch Institute for Integrative Cancer Research at MIT (/ˈkk/ KOHK; also referred to as the Koch Institute, KI, or CCR/KI) is a cancer research center affiliated with the Massachusetts Institute of Technology (MIT) located in Cambridge, Massachusetts, United States. The Institute is one of eight National Cancer Institute-designated basic research centers in the United States.

The Institute was launched in October 2007 with a $100 million grant from David H. Koch and the 180,000 square feet (17,000 m2) research facility opened in December 2010, replacing the MIT Center for Cancer Research (CCR). The Institute is affiliated with 25 MIT faculty members in both the Schools of Engineering and Science.

In 1974, the Center for Cancer Research was founded by 1969 Nobel Laureate Salvador Luria to study basic biological processes related to cancer. The Center researches the genetic and molecular basis of cancer, how alterations in cellular processes affect cell growth and behavior, and how the immune system develops and recognizes antigens. The CCR was both a physical research center as well as an organizing body for the larger MIT cancer research community of over 500 researchers. Financial support for the CCR primarily came from Center Core grant from the National Canter Institute as well as research project grants from the National Institutes of Health, Howard Hughes Medical Institute, and foundation support. The CCR research groups were successful in identifying oncogenes, immunology of T lymphocytes, and roles of various cellular proteins. The CCR produced four Nobel Laureates: David Baltimore (1975), Susumu Tonegawa (1987), Phillip Sharp (1993), and H. Robert Horvitz (2002).


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