"DNA" is a song recorded by British girl group Little Mix for their 2012 debut album of the same name. Released as the album's second single, the song was solicited to contemporary radio stations in the United Kingdom on 1 October 2012. Syco digitally released the single in Ireland and the United Kingdom on 9 November 2012. It was written by TMS, Iain James and Little Mix, while the production was handled by TMS. "DNA" is an electropop and R&B ballad, which incorporates dubstep musical styles. Lyrically, the song contains multiple references to scientific vocabulary and is based on themes of love and obsession.

"DNA" garnered positive reviews from music critics, who praised the group's powerful vocals and the song's darker sound. The song received comparisons to Katy Perry's song "E.T." (2011), which was an inspirational factor in its development. "DNA" was commercially successful, debuting and peaking at number three the UK Singles Chart with sales of 72,044 copies, becoming the group's third consecutive top three hit there. It also reached the top ten in Ireland, Hungary and Scotland, and was certified gold in Australia where it peaked at number 48.

The accompanying music video was directed by Sarah Chatfield and was released on 19 October 2012. Filmed in comic book movie style, it portrays Little Mix as female assassins who stalk and then kidnap men who they are obsessed with. Critics noted the similarities from the video with that of comic series Sin City and fictional character Catwoman, and gave it positive reviews for it. Little Mix have performed "DNA" on television shows Loose Women and The X Factor. They also performed the song as a continuation of the music video's storyline on their DNA Tour (2013).

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