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Cyclin dependent kinase inhibitor

Cyclin-dependent kinase inhibitor
PDB 1jsu EBI.jpg
Structure of the p27Kip1 cyclin-dependent-kinase inhibitor bound to the cyclin A-Cdk2 complex.
Identifiers
Symbol CDI
Pfam PF02234
InterPro IPR003175
SCOP 1jsu
SUPERFAMILY 1jsu

A cyclin-dependent kinase inhibitor protein is a protein which inhibits cyclin-dependent kinase. Several function as tumor suppressor proteins. Cell cycle progression is negatively controlled by cyclin-dependent kinases inhibitors (called CDIs, CKIs or CDKIs). CDIs are involved in cell cycle arrest at the G1 phase.



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