"Cousin Dupree" is the first single from Steely Dan's 2000 album Two Against Nature. The song describes the desire a young man (Dupree) has for his attractive cousin. In 2001, the song won a Grammy Award for Best Pop Performance by a Duo or Group with Vocal.

In July 2006, Steely Dan posted a humorous letter on their website, saying that the title of Owen Wilson's film You, Me, and Dupree, is stolen from their song. The film is about a house guest who overstays his welcome; the song's title character is a slacker who is sleeping on his aunt's couch. Owen Wilson defended himself in similarly deadpan comic fashion, stating "I have never heard the song 'Cousin Dupree' and I don't even know who this gentleman, Mr. Steely Dan, is. I hope this helps to clear things up and I can get back to concentrating on my new movie, 'HEY 19.'"

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