The characters of the ABC show Once Upon a Time and its spin-off Once Upon a Time in Wonderland are related to classic fairy tale and fantasy characters, and often tie-in with other Disney media properties.
As a young child, she unintentionally tells Regina's mother a secret involving Regina's secret relationship with the stable boy, causing Cora to kill him and Regina to become the Evil Queen. Since then, she had been on the run from her, eventually meeting Prince David, who she nicknames as Charming. She is later placed under a sleeping curse by the Evil Queen but broken by Charming. The two get married, but is threaten by the Evil Queen with a curse. In order to defeat her, Snow and Charming send their daughter Emma to the Land Without Magic.
In Storybrooke, she appears as Mary Margaret Blanchard, a teacher at Storybrooke Elementary School. After the curse broke, she is reunited with Charming, now known as David, as well as her daughter Emma and grandson Henry. She is responsible for the death Regina's mother. Later, she follows the rest of the heroes to Neverland to save Henry and is eventually sent back to the Enchanted Forest after Regina undid her curse. She later cast the curse to bring everyone back to Storybrooke to protect her unborn child from the Wicked Witch of the West. She also clashes with Maleficent after Maleficent threatens to reveal a dark secret of her past. After Emma becomes the Dark One, she goes to Camelot with the heroes to help save her and later to the Underworld with Emma to save Hook. She also accidentally gets send to the Land of Untold Stories with David, Hook and Zelena, but is eventually brought back to Storybrooke.
Emma is born in the Enchanted Forest, but is sent to the Land Without Magic to break a curse in twenty-eight years. Years later, she meets Neal Cassidy and results in the birth of her son who she gives up for adoption. Ten years later, she is found by Henry, her son, and brought to Storybrooke to break a curse.
In Storybrooke, at first, she thinks Henry is crazy, but eventually believes in the curse and brakes it, earning the title as the Savior. She is reunited with her parents David and Mary Margaret. Later, she finds out that Neal is also from the Enchanted Forest and the son of Rumplestiltskin. After Henry is kidnapped and brought to Neverland, she goes with the heroes to save him, leading to a new curse being cast in Storybrooke and forcing Regina to undo the curse. Emma and Henry is left behind and lives a normal life in New York City. She is later brought back to Storybrooke by Hook to defeat the Wicked Witch of the West. Later, after ending up in the past, she accidentally brings Elsa to Storybrooke where she finds out that Elsa's aunt, Ingrid, was her foster mother. In a bid to turn her dark, Mr. Gold manipulates events resulting in her killing Cruella. Emma later becomes the Dark One but is reverted by Hook who sacrifices himself. She leads the heroes to the Underworld to rescue Hook. When the Land of Untold Stories refugees ends up in Storybrooke, she teams up with Henry to help them, and clashes with Regina's former evil self — the Evil Queen (Serum).