Combretastatin B-1

Combretastatin B-1

Names
IUPAC name 3-methoxy-6-[2-(3,4,5-trimethoxyphenyl)ethyl]benzene-1,2-diol
Other names Combretastatin B1
Identifiers
CAS Number	109971-64-4
3D model (Jmol)	Interactive image Interactive image
ChemSpider	119539
PubChem CID	135716
InChI InChI=1S/C18H22O6/c1-21-13-8-7-12(16(19)17(13)20)6-5-11-9-14(22-2)18(24-4)15(10-11)23-3/h7-10,19-20H,5-6H2,1-4H3 Key: ZSNYQENLWQYSRK-UHFFFAOYSA-N InChI=1/C18H22O6/c1-21-13-8-7-12(16(19)17(13)20)6-5-11-9-14(22-2)18(24-4)15(10-11)23-3/h7-10,19-20H,5-6H2,1-4H3 Key: ZSNYQENLWQYSRK-UHFFFAOYAW
SMILES COC1=C(C(=C(C=C1)CCC2=CC(=C(C(=C2)OC)OC)OC)O)O O(c1cc(cc(OC)c1OC)CCc2ccc(OC)c(O)c2O)C
Properties
Chemical formula	C18H22O6
Molar mass	334.36 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

Combretastatin B-1 is a combretastatin and a dihydrostilbenoid. It can be found in Combretum caffrum, the Eastern Cape South African bushwillow tree or in Combretum kraussii, the forest bushwillow.

It can be produced by selective hydrogenation of Combretastatin A-1.

It is a potent inhibitor of microtubule assembly in vitro.