Colonia Guerrero is a colonia of Mexico City located just north-northwest of the historic center. Its borders are formed by Ricardo Flores Magón to the north, Eje Central Lazaro Cardenas and Paseo de la Reforma to the east, Eje1 Poniente Guerrero to the west and Avenida Hidalgo to the south. The colonia has a long history, beginning as an indigenous neighborhood in the colonial period called Cuepopan. The origins of the modern colonia begin in the first half of the 19th century, but most of its development occurred as a residential area in the late 19th and early 20th. Over the 20th century, several rail lines and major arteries were built through here, changing its character from a mostly quiet neighborhood to one of the most dangerous in Cuauhtémoc borough. It is home to two early colonial era churches, the Franz Mayer Museum and one Neo-Gothic church from the Porfirian era.
Although the Santa Veracruz Church, the Franz Mayer Museum and the San Hipólito Church are associated with the historic center of the city due to their locations along Hidalgo Street, they are officially located in Colonia Guerrero. The Santa Veracruz Church is one of the oldest religious establishments in Mexico City and was the third most important church in the area in the 16th century. It was established by a religious brotherhood founded by Hernán Cortés.The parish church was originally built in 1586, but this building was replaced in the 18th century to the one standing today. The former monastery building and hospital now house the Franz Mayer Museum, but the church still maintains its original function. Most of its interior decorations are gone, but it is still home to two important images, the Christ of the Seven Veils and the Virgin of the Remedies (also called La Gachupina).The church is located on the east side of the Plaza of Santa Veracruz, between 2 de Abril and Valeriano Trijillo Streets facing Hidalgo Street and the Alameda Central .