References to an expulsion of Jews from Rome by the Roman Emperor Claudius, who was in office AD 41-54, appear in the Acts of the Apostles (), and in the writings of Roman historians Suetonius (c. AD 69 – c. AD 122), Cassius Dio (c. AD 150 – c. 235) and fifth-century Christian author Paulus Orosius. Scholars generally agree that these references refer to the same incident.
The exact date is uncertain. The maximal time window for the expulsion of Jews from Rome is from January AD 41 until January AD 53. More detailed estimates such as those based on the AD 49 date by Orosius or the reduction of the AD 53 upper limit due to Proconsul Gallio's health are possible but controversial.
There were at least two expulsions of Jews from Rome before this event. In 139 BC the Jews were expelled after being accused of aggressive missionary efforts. Then in AD 19 Tiberius once again expelled Jews from the city for similar reasons.
The author of the Acts of the Apostles () explains how the Apostle Paul met Priscilla and Aquila and mentions in passing an expulsion of Jews from Rome:
"After this, Paul left Athens and went to Corinth. 2 There he met a Jew named Aquila, a native of Pontus, who had recently come from Italy with his wife Priscilla, because Claudius had ordered all Jews to leave Rome. Paul went to see them, 3 and because he was a tentmaker as they were, he stayed and worked with them. 4 Every Sabbath he reasoned in the synagogue, trying to persuade Jews and Greeks.
5 When Silas and Timothy came from Macedonia, Paul devoted himself exclusively to preaching, testifying to the Jews that Jesus was the Messiah. 6 But when they opposed Paul and became abusive, he shook out his clothes in protest and said to them, “Your blood be on your own heads! I am innocent of it. From now on I will go to the Gentiles.”
7 Then Paul left the synagogue and went next door to the house of Titius Justus, a worshiper of God. 8 Crispus, the synagogue leader, and his entire household believed in the Lord; and many of the Corinthians who heard Paul believed and were baptized.
9 One night the Lord spoke to Paul in a vision: “Do not be afraid; keep on speaking, do not be silent. 10 For I am with you, and no one is going to attack and harm you, because I have many people in this city.” 11 So Paul stayed in Corinth for a year and a half, teaching them the word of God.