The City of Port Adelaide was a local government area of South Australia centred at the port of Adelaide.
The council of Port Adelaide was established on 27 December 1855 when Port Adelaide was declared a Corporate Town centred on the port of Adelaide, which had been opened some years prior in 1837. From 1884 to 1900 the adjacent district councils of Portland Estate, Birkenhead, Alberton and Queenstown, and Rosewater, and the Corporate Town of Semaphore, were amalgamated with the Town of Port Adelaide, dramatically increasing its size. On 23 May 1901, Port Adelaide was proclaimed a city by Governor Tennyson and became the City of Port Adelaide.
From the late 1830s to 1945, the area surrounding Port Adelaide was subdivided into many small district areas as owners bought, subdivided and sold areas of land. As the areas became smaller, and more landowners named their own estates, the number of these early "suburbs" reached 90.
By the 1940s the number of suburbs was becoming a problem, so the Port Adelaide Council moved to reduce the number of local district areas to 18, in 1945. The boundaries and names of the suburbs were further stabilised when postcodes were introduced to Australia in 1967.
In March 1996 the City of Port Adelaide merged with the City of Enfield to form the new City of Port Adelaide Enfield.