Francesco (Cicco) Simonetta (1410 – 30 October 1480) was an Italian Renaissance statesman. He also is remembered for composing an early treatise on cryptography.
Francesco, nicknamed Cicco, was born in Caccuri, Calabria, and received a fine education. He studied Latin, Greek, Hebrew, and other languages and graduated in civil and canonic law, presumably in Naples.
As a young man, he entered the service of the Sforza family as a secretary to condottiero Francesco Sforza and rapidly rose to the top of the administration. He was soon placed in charge of the city of Lodi.
In 1441, Francesco Sforza married Bianca Maria Visconti (1425–1468), illegitimate daughter of Filippo Maria Visconti, 3rd Duke of Milan. On Filippo’s death (1447), the so-called Ambrosian Republic had been set up in Milan by the patrician families. In 1450, Francesco Sforza, backed by the Venetians, laid siege to Milan to combat the aristocrats. The city surrendered after eight months and Francesco made himself ‘‘Capitano del popolo.’’ He was proclaimed duke by the people and by right of his wife.
Simonetta was nominated "golden knight" and entered the ducal chancellery. This appointment was the beginning of his undisputed domination of the political situation for thirty years. As a reward for his services, he was given the fief of Sartirana, in Lomellina, which he administered with competency and care. He soon became a member of the Secret Council. When he married Elisabetta Visconti in 1452 his fame was widespread.