Christian III Maurice, Duke of Saxe-Merseburg (Merseburg, 7 November 1680 – Merseburg, 14 November 1694), was a duke of Saxe-Merseburg and member of the House of Wettin.
He was the eldest son of Christian II, Duke of Saxe-Merseburg, and Erdmuthe Dorothea of Saxe-Zeitz.
At the age of thirteen, Christian Maurice succeeded his father upon his death on 20 October 1694. During his minority, the Elector Frederick August I of Saxony took over the administration of the duchy as regent. However, the custody of the young duke was mainly the responsibility of his mother, the dowager duchess Erdmuthe Dorothea, who also took an interest in governing the duchy.
The new duke died of smallpox after reigned for only twenty-five days and was succeeded by his younger brother Maurice Wilhelm.