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Cholesterolosis of the gallbladder

Cholesterolosis of gallbladder
Gallbladder cholesterolosis low mag.jpg
Micrograph of cholesterolosis of the gallbladder. H&E stain.
Classification and external resources
Specialty gastroenterology
ICD-10 K82.4
ICD-9-CM 575.6
DiseasesDB 31524
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In surgical pathology, strawberry gallbladder, more formally cholesterolosis of the gallbladder and gallbladder cholesterolosis, is a change in the gallbladder wall due to excess cholesterol.

The name strawberry gallbladder comes from the typically stippled appearance of the mucosal surface on gross examination, which resembles a strawberry. Cholesterolosis results from abnormal deposits of cholesterol esters in macrophages within the lamina propria (foam cells) and in mucosal epithelium. The gallbladder may be affected in a patchy localized form or in a diffuse form. The diffuse form macroscopically appears as a bright red mucosa with yellow mottling (due to lipid), hence the term strawberry gallbladder. It is not tied to cholelithiasis (gallstones) or cholecystitis (inflammation of the gallbladder).

Cholesterolosis of the gallbladder (gross image)

Micrograph of cholesterolosis of the gallbladder

Micrograph of cholesterolosis of the gallbladder

Micrograph of cholesterolosis of the gallbladder


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