"Cherokee Rose" is the fourth episode of the second season and 10th episode overall of the post-apocalyptic horror television series The Walking Dead, which aired on AMC in the United States on November 6, 2011. The episode was written by Evan Reilly and directed by Billy Gierhart. In the episode, the group of survivors move to the home of Hershel Greene (Scott Wilson). While the group contemplates on what to do, Daryl Dixon (Norman Reedus) continues to search for Sophia Peletier (Madison Lintz).

Major themes in "Cherokee Rose" includes Daryl Dixon's gradual change into a lighter character and the beginning of his close relationship with Carol Peletier and the developing romantic relationship between Maggie and Glenn. Principal photography for the episode commenced in Coweta County, Georgia, where filming locations were set up in an abandoned late nineteenth century Gothic revival home in Senoia, Georgia and in downtown Sharpsburg, Georgia.

During a sequence in the episode, the survivors pull a bloated zombie—commonly referred to by the group as a "walker"—out of a water well, ultimately leading to the walker splitting apart. Greg Melton, the series' production designer, collaborated with KNB Efx Group in producing the scene. Filming for the sequence arose over an approximate period of two days.

"Cherokee Rose" was well received by television critics, who praised the episode's storylines and character development. Upon initial airing, it garnered 6.29 million viewers and attained a 3.4 rating in the 18-49 demographic, according to Nielsen ratings. "Cherokee Rose" became the highest-rated cable program of the day, as well as the second highest-rated cable program of the week.

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