Charles Frederick Ashley Cooper Ponsonby, 2nd Baron de Mauley of Canford (12 September 1815 – 24 August 1896) was a British peer and Liberal politician.
Ponsonby was the son of the first Lord de Mauley, third son of the third Earl of Bessborough, and Lady Barbara Ashley-Cooper, only child and heiress of the fifth Earl of Shaftesbury. He attended Trinity College, Cambridge.
On 9 August 1838, he married his cousin, Lady Maria Ponsonby (a daughter of John Ponsonby, 4th Earl of Bessborough) and they had at least six children: