Charles II, Duke of Bourbon (Château de Moulins, 1434–September 13, 1488, Lyon), was Archbishop of Lyon from an early age and a French diplomat under the rule of Louis XI of France. He had a 2-week tenure as Duke of Bourbon in 1488, being ousted afterward by his younger brother and successor, Peter II, Duke of Bourbon.
An hereditary member of the House of Bourbon through Charles I, Duke of Bourbon and Agnes of Burgundy, Charles II, being a younger son, was appointed Canon of Lyon in 1443 and soon after, in June 6, 1444, elected Archbishop of Lyon at the age of 11. This election followed the death of Amedée de Talaru and the renunciation of John III of Bourbon, illegitimate offspring of his grandfather John I, Duke of Bourbon. His office was confirmed by Pope Eugene IV in November 14, 1446 after the death of Geoffroy Vassal, Archbishop of Vienne who the pope had first appointed in disregard of the Pragmatic Sanction in 1444. Due to his age, Charles II's archiepiscopate was administered in succession by Jean Rolin, bishop of Autun, from 1446 to 1447, Du Gué, bishop of Orléans, from 1447 to 1449, and John III of Bourbon, bishop of Puy, from 1449 to 1466.