Charles Gerard, 2nd Earl of Macclesfield (c. 1659 – 5 November 1701) was an English peer, soldier and MP.
He was born in France, the eldest son of Charles, 1st Baron Gerard of Brandon, and Jeanne, the daughter of Pierre de Civelle, equerry to Queen Henrietta Maria. He became an English national by Act of Parliament in 1677.
By 1678 he was a Lieut-Colonel in Lord Gerard's Horse and a full colonel in 1679. That year he entered politics, being elected knight of the shire for Lancashire in both March and October, and again in 1681.
Like his father Charles, the 1st Earl, he was involved in the intrigues of the Duke of Monmouth. In 1685 he was sentenced to death for being a party to the Rye House Plot, but was pardoned by Charles II. In 1689 he was re-elected Member of Parliament for Lancashire, which he represented till 1694, when he succeeded to his father's peerage. He was Custos Rotulorum for Lancashire from 1689 until his death in 1701.
Having become a major-general in 1694, Macclesfield saw some service abroad, and in 1701 he was selected first commissioner for the investiture of the elector of Hanover (afterwards King George I) with the order of the Garter, on which occasion he also was charged to present a copy of the Act of Settlement to the dowager electress Sophia.
He died suddenly on 5 November 1701 at about 40 years old, leaving no legitimate children.
In March 1698, Macclesfield was divorced from his wife Anna, daughter of Sir Richard Mason of Sutton, by Act of Parliament; the first occasion on which a divorce was so granted without a previous decree of an ecclesiastical court. The countess was the mother of two children who were known by the name of Savage, and whose reputed father was Richard Savage, 4th Earl Rivers. The poet Richard Savage claimed that he was the younger of these children. The divorced countess married Colonel Henry Brett about the year 1700, and died at the age of eighty-five in 1753. Her daughter, Anna Margaretta Brett, was a mistress of George I. The 2nd earl of Macclesfield was succeeded by his brother Fitton Gerard, 3rd Earl (c. 1665–1702), on whose death without heirs the title became extinct in December 1702.