Celebrity Fifteen to One is a celebrity version of the Channel 4 game show Fifteen to One. William G. Stewart presented the first two episodes, which were Christmas specials that aired on 27 December 1990 and 30 December 1992, and Adam Hills has hosted subsequent episodes on 20 September 2013, 6, 13, 20 and 27 June 2014, a Christmas special on 23 December 2014 and 7, 14, 21 and 28 August 2015. Richard Whiteley, Anna Raeburn, Sally Jones and Rory McGrath appeared on both 1990s episodes, with Alex Brooker, Jimmy Carr, Johnny Vegas, Rhod Gilbert and Gyles Brandreth also having made appearances on more than one episode. Of these, Brandreth is the only person to have made appearances on episodes presented by both hosts.
The first episode was broadcast on 27 December 1990. The format is largely the same as that of Fifteen to One, though with the Barry Cryer rule: Those who get both questions wrong may still play round 2 with one life remaining, with Cryer being the only one to miss both questions. The programme is extended to 45 minutes from 30, with an extra advert added between the first and second rounds.
A second celebrity special aired on 30 December 1992. In his book "A Matter of Facts: An Insider's Guide To Quizzing", contestant Marcus Berkmann, who had previously appeared on a civilian episode of the show two years prior, explained that he was asked to appear on the program after Vincent Hanna pulled out, and noted that "clearly some barrels had been scraped for this, and [he] was at the bottom of the very last barrel". The winner, Patrick Stoddart, won by taking a step back from the rest of the semi-circle, resulting in no-one nominating him in round 2. This would be the last celebrity Fifteen to One for over twenty years.