Caspase 4
| caspase 4, apoptosis-related cysteine peptidase | |
|---|---|
| Identifiers | |
| Symbol | CASP4 |
| Alt. symbols | ICE(rel)II, ICH-2, TX |
| Entrez | 837 |
| HUGO | 1505 |
| OMIM | 602664 |
| RefSeq | NM_001225 |
| UniProt | P49662 |
| Other data | |
| EC number | 3.4.22.57 |
| Locus | Chr. 11 q22.2-q22.3 |
Caspase 4 is an enzyme that proteolytically cleaves other proteins at an aspartic acid residue (LEVD-), and belongs to a family of cysteine proteases called caspases. The function of caspase 4 is not fully known, but it is believed to be an inflammatory caspase, along with caspase 1, caspase 5 (and the murine homolog caspase 11), with a role in the immune system.
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