Among the variety of ways cannabis is consumed, forms of smoking or oral consumption are most common. Each method leads to subtly different psychoactive effects due to the THC and other chemicals being activated, and then consumed through different administration routes. It is generally considered that smoking, which includes combustion toxins, produces a somewhat more relaxing ("stoned") effect, while eating delays the onset of effect but the duration of effect is typically longer. In a 2007 ScienceDaily report of research conducted at University of California–San Francisco, researchers reported that vaporizer users experience the same biological effect, but without the toxins associated with smoking.
Cannabis can be smoked with implements such as bongs, hookahs, and pipes. Makeshift pipes or commercial pipes may be used, or cigarette-like joint or cigar-like blunt may be smoked.
Local methods have differed by the preparation of the cannabis plant before use, the parts of the cannabis plant that are used, and the treatment of the smoke before inhalation. In early times, as in some parts of Africa today, a pile of cannabis was simply laid on a fire and the smoke inhaled.
A vaporizer heats herbal cannabis to 157–210 °C (315–410 °F), which causes the active ingredients to evaporate into a gas without burning any plant material (the boiling point of THC is 157 °C (315 °F). Vaporizing releases a lower proportion of carbon monoxide and other toxic chemicals than does smoking, although the proportion may vary depending on the design of the vaporizer and the temperature at which it is set. A MAPS-NORML study using a Volcano vaporizer reported 95% THC and no toxins delivered in the vapor. An older study using less sophisticated vaporizers found some toxins.
A pocket-sized form of vaporizer is available as of September 2013—one particular model uses a rechargeable battery, is constructed from wood, and features a removable cover. Typically, portable vaporizers can only be used for liquids, feature pre-soaked wicks, and require the user to operate a cartridge.