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Canarypox

Canarypox virus
Virus classification
Group: Group I (dsDNA)
Family: Poxviridae
Subfamily: Chordopoxvirinae
Genus: Avipoxvirus
Species: Canarypox virus

Canarypox virus (CNPV) is an Avipoxvirus and etiologic agent of canarypox, a disease of wild and captive birds that can cause significant losses. Canarypox can enter human cells, but it cannot survive and multiply in human cells. There is a live viral vaccine available which may have beneficial properties against human cancer when used as a mammalian expression vector. (ATCvet code: QI01KD01 (WHO)). Furthermore, the POXIMUNE® C vaccine does offer direct protection against CNPV in susceptible birds.

Generally CNPV is considered a disease of songbirds, such as canaries, magpies and nightingales, and is associated with higher mortality rates when compared to other avian pox viruses. In some instances, mortality approaches 100%. Avian pox viruses also cause significant economic losses in domestic poultry and remain a problem in the conservation of endemic bird species inhabiting islands.

The general symptoms of CNPV are similar to those of other species of avian pox viruses and are characterised by pustules and diphtheria or pneumonia-like symptoms.

Canarypox virus (CNPV) is a member of the Poxviridae family. Canarypox viruses, as with other bird pox viruses, are in the genera of Avipoxvirus. Nine other species are also in the genus Avipoxvirus. These include: Fowlpox virus, Juncopox virus, Mynahpox virus, Psittacinepox virus, Sparrowpox virus, Starlingpox virus, Pigeonpox virus, Turkeypox virus and Quailpox virus.

It has thus far been reported that around 232 bird species (from 23 disparate orders) are affected by avian pox virus.


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