The Gospel of John refers a number of times to a town called Cana of Galilee (Greek: κανα της γαλιλαιας).
Among Christians and other students of the New Testament, Cana is best known as the place where, according to the Fourth Gospel, Jesus performed "the first of his signs", his first public miracle, the turning of a large quantity of water into wine at a wedding feast (John 2:1–11) when the wine provided by the bridegroom had run out. Although none of the synoptic gospels record the event, mainstream Christian tradition holds that this is the first public miracle of Jesus.
The other biblical references to Cana are also in John: John 4:46, which mentions that Jesus is visiting Cana when he is asked to heal the son of a royal official at Capernaum; and John 21:2, where it is mentioned that Nathanael (sometimes identified with the Bartholomew included in the synoptic gospels' lists of apostles) comes from Cana. The Book of Joshua mentions one city (19:28) and one brook (16:8; 17:9) named Cana – neither is likely to be the Cana of Galilee.
In secular history, the annals of Assyrian king Tiglath-Pileser III, who conquered the Galilee in a 733 BC campaign, contain a badly preserved list of cities that had been thought to mention a certain Kana. It relates 650 captives were taken there. However, a revised transliteration revealed the one well-preserved syllable to be Ku, not Ka.