"Can't Hold Us" is a song written and performed by American hip hop duo Macklemore & Ryan Lewis and singer Ray Dalton, originally released on August 16, 2011 as the second single from the duo's debut studio album The Heist (2012).

The song became a sleeper hit and reached number one on the Billboard Hot 100, making it their second number-one hit in the United States. It is also their third consecutive number-one single in Australia. The music video was nominated for Best Music Video at the 56th Annual Grammy Awards in 2014. The song was also listed as "The Most-Streamed Song of 2013" by Spotify.

The song is in the key of E minor with a tempo set at 146 beats per minute. The radio edit cuts out portions of the introduction, as well as the extended bridge section and an alternate beat during the last chorus, replacing them with an introduction from Dalton and a clapping beat. The beat is similar to their live performances of the song.

"Can't Hold Us" was generally well received by music critics. Lewis Corner of Digital Spy gave the song four stars out of five, praising its "infectious, soul-soaked piano line and beats more vibrant than Rio de Janeiro's finest carnival floats". Writing for The Edge, Hannah Mylrea rated the song 9/10 and complemented the duo's dynamism, deeming it "another massive summer hit".AllMusic's David Jeffries also gave it four stars on five and wrote: "Macklemore & Ryan Lewis combine the handclapping, foot-stomping, and propulsive rhythms of old-fashioned gospel music with an infectious, uplifting chorus that could have been ripped straight out of will.i.am's playbook...this motivational, "this is the moment" number is identifiably and lovably Macklemore."

Due to the major international success of the duo's "Thrift Shop", there was a resurgence in sales of their previous singles and their album The Heist.

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