Calle Ramón Emeterio Betances

Calle Ramón Emeterio Betances (Dr. Ramón Emeterio Betances Street) is the most long urban road in Mayagüez, serving as the Main Street of Mayagüez. It corresponds with the former Post Street's south of Yagüez River section.

The Ramón Emeterio Betances Street starts at the Barcelona Gate of the University of Puerto Rico at Mayagüez (UPRM) where a flagpole is placed with the Puerto Rican flag aside a José De Diego iron bust. It states that the Recinto Universitario de Mayagüez (as UPRM is named officially in Spanish) was founded as Colegio de Agricultura y Artes Mecánicas (CAAM) by José De Diego on September 23, 1911.

Just facing the UPRM's Barcelona Gate is a junction where merges the Alfonso Valdés Cobián Boulevard and Pedro Albizu Campos Avenue aside with the Parque de los Próceres. In this point the road runs over a 6-lane bridge over the Yagüez River going southbound to Barcelona Sector, where some fast foods, a gas station, shops and pubs like the legendary El Garabato are located. The Radiocentro Building is located next, marking the entrance to Calle Bosque (a student gathering social zone, where are located many college student's lodgings and apartments buildings).

Going south way, the Ramón Emeterio Betances Street passes the Millonarios Street (now named Calle Ramón Sánchez Justiniano) which marks the entrance to former Hacienda Guenard and the beginning of the historical downtown zone. Here is placed the Hospital San Antonio, founded by Dr. Ramón Emeterio Betances in 1865 with citizen fund-raising. Near is located the Hospital Perea (old Brothers Perea's Clinic) and El Cacique lounge.

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