Call–Exner bodies are small eosinophilic fluid-filled spaces between granulosa cells. The granulosa cells are usually arranged haphazardly around the space.
They are pathognomonic for Granulosa cell tumors.
They are composed of membrane-packaged secretion of granulosa cells and have relations to the formation of liquor folliculi which are seen among closely arranged granulosa cells.
They are named for Emma Louise Call (1847-1937), an American Physician, and Sigmund Exner.