CCL23

chemokine (C-C motif) ligand 23
Identifiers
Symbol	CCL23
Alt. symbols	SCYA23, Ckb-8, MPIF-1, MIP-3, CKb8
Entrez	6368
HUGO	10622
OMIM	602494
PDB	1G91
RefSeq	NM_005064
UniProt	P55773
Other data
Locus	Chr. 17 q11.2

Chemokine (C-C motif) ligand 23 (CCL23) is a small cytokine belonging to the CC chemokine family that is also known as Macrophage inflammatory protein 3 (MIP-3) and Myeloid progenitor inhibitory factor 1 (MPIF-1). CCL23 is predominantly expressed in lung and liver tissue, but is also found in bone marrow and placenta. It is also expressed in some cell lines of myeloid origin. CCL23 is highly chemotactic for resting T cells and monocytes and slightly chemotactic for neutrophils. It has also been attributed to an inhibitory activity on hematopoietic progenitor cells. The gene for CCL23 is located on human chromosome 17 in a locus containing several other CC chemokines. CCL23 is a ligand for the chemokine receptor CCR1.

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