CCL15

chemokine (C-C motif) ligand 15
Identifiers
Symbol	CCL15
Alt. symbols	SCYA15, HCC-2, NCC-3, SCYL3, MIP-5, Lkn-1, MIP-1d, HMRP-2B
Entrez	6359
HUGO	10613
OMIM	601393
PDB	2HCC
RefSeq	NM_032965
UniProt	Q16663
Other data
Locus	Chr. 17 q11.2

Chemokine (C-C motif) ligand 15 (CCL15) is a small cytokine belonging to the CC chemokine family that is also known as leukotactin-1, MIP5 and HCC-2. CCL15 is expressed in liver, small intestine, colon, and in certain leukocytes and macrophages of the lung. It is chemotactic for neutrophils, monocytes, and lymphocytes and elicits its effects by binding to cell surface chemokine receptors like CCR1 and CCR3. The human CCL15 gene spans four exons and is located in a head-to-tail orientation on chromosome 17 with the gene of another CC chemokine known as CCL14.