chemokine (C-C motif) ligand 1 | |
---|---|
Identifiers | |
Symbol | CCL1 |
Alt. symbols | SCYA1, I-309, TCA3, P500, SISe |
Entrez | 6346 |
HUGO | 10609 |
OMIM | 182281 |
PDB | 1EL0 |
RefSeq | NM_002981 |
UniProt | P22362 |
Other data | |
Locus | Chr. 17 q11.2 |
Chemokine (C-C motif) ligand 1 (CCL1) is a small glycoprotein secreted by activated T cells that belongs to a family inflammatory cytokines known as chemokines. CCL1 attracts monocytes, NK cells, and immature B cells and dendritic cells by interacting with a cell surface chemokine receptor called CCR8. This chemokine resides in a large cluster of CC chemokines on human chromosome 17.