Burton Mere Wetlands (grid reference SJ304744) is a nature reserve on the Dee Estuary straddling the border between Cheshire, England and Flintshire, Wales. It is run by the Royal Society for the Protection of Birds (RSPB) and incorporates the older Inner Marsh Farm reserve. It lies near the village of Burton, about 3 km south of Neston. It has all been developed by the RSPB and includes a large area of mixed wetland habitats, bluebell woodlands, and arable fields all managed to attract wildlife.
The reserve is open from 9am until 9pm (or dusk if sooner) and the reception hide is open from 9:30am until 5pm. There is a charge for non-members of the RSPB.
The site consisted of tidal mudflats until the late 19th century when it was reclaimed during the building of the Wrexham to Bidston railway line. The resulting land was used for grazing and duck shooting and was later used for arable farming.
The RSPB bought land for the original Inner Marsh Farm reserve in 1986 and the reserve opened in June 1992. Three shallow, freshwater pools were created as well as a footpath leading to a hide overlooking the pools. Because of restrictions from the local council, the RSPB did not publicise the reserve and access was originally for members only. The reserve was closed on Tuesdays for essential maintenance. There was a small car park at the end of an untarmacked road, signposted for Burton Point Farm, off Station Road.
The reserve was enlarged by the purchase of land at Burton Marsh Farm in 2006 and Burton Mere Fisheries in 2008. New wetland areas were created along with additional visitor facilities including a reception hide, toilet block and a new entrance and car park. The reserve was renamed Burton Mere Wetlands in September 2011 when the new section was officially opened by the television presenter and naturalist Iolo Williams. Further paths and screens including a path linking the old and new sections of the reserve were opened in April 2014.