Bufalin

Bufalin

Names
IUPAC name (3β,5β)-3,14-Dihydroxybufa-20,22-dienolide
Identifiers
CAS Number	465-21-4
3D model (JSmol)	Interactive image
ChemSpider	7826155
InChI InChI=1S/C24H34O4/c1-22-10-7-17(25)13-16(22)4-5-20-19(22)8-11-23(2)18(9-12-24(20,23)27)15-3-6-21(26)28-14-15/h3,6,14,16-20,25,27H,4-5,7-13H2,1-2H3/t16-,17+,18-,19+,20-,22+,23-,24+/m1/s1 Key: QEEBRPGZBVVINN-BMPKRDENSA-N
SMILES C[C@]12CC[C@@H](C[C@H]1CC[C@@H]3[C@@H]2CC[C@]4([C@@]3(CC[C@@H]4c5ccc(=O)oc5)O)C)O
Properties
Chemical formula	C24H34O4
Molar mass	386.53 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

Bufalin, is a cardiotonic steroid originally isolated from the Chinese toad venom. It is a component found in many Chinese traditional medicine.

Bufalin has a in vitro antitumor effects against various malignancies, including hepatocellular and lung carcinoma. However, as with other bufadienolides, its use is hampered by its cardiotoxicity.