"Brother's Keeper" is the pilot episode of the first season of the American television series Miami Vice. The episode premiered on September 16, 1984 with a two-hour (including commercials) season premiere. The episode was received well critically, winning two out of three Emmy awards for which it was nominated.

NBC would rebroadcast the episode in 2006 during the opening weekend for executive producer/director Michael Mann's theatrical reboot starring Colin Farrell and Jamie Foxx.

James "Sonny" Crockett (Don Johnson) is a Metro-Dade vice detective who has just lost his colleague Eddie Rivera (Jimmy Smits) at a car bombing, when they were trying to arrest a small-time drug dealer. He also is in the middle of an ugly divorce, since his wife can't stand the stress of having a husband working undercover with criminals.

Crockett is investigating a Colombian drug dealer, named Calderone (Miguel Piñero), when he meets a New York police detective named Rafael Tubbs (Philip Michael Thomas). Since they are having problems approaching Calderone due to a traitor (leading Tubbs to say "You've got a leak in your department the size of the East River"), Crockett and Tubbs team up, after a suggestion from Crockett's Lieutenant Rodriguez (Gregory Sierra) to work together, even though they don't like each other.

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