"Break Up" is the first single from Mario's fourth studio album D.N.A.. It features and was co-written by Gucci Mane and Sean Garrett with production and additional writing from Shondrae "Bangladesh" Crawford. The single was first premiered on the radio station V-103 at March 30, 2009 with Greg Street.

According to Mario, "it's a little bit of everything on this record. That’s why I love it. Sean is like a brother to me. He knows me. So, when he did this record, he was definitely thinking about me. It’s a club record and every man has experienced this situation before. It’s like why would you want to break up with me when you gon’ get the same thing with the next man. But, he ain’t gon do it as fly as I can. I can’t wait to perform it. It’s going to be a movie. Look for the movie! We’re not calling this a single or a video, we’re calling it a movie."

The song, mixed by Fabian, was composed using a loop from Image-Line's FL Studio software named "flute riff." The drums are simplistic and resemble Bangladesh's previous productions such as Beyoncé's "Diva" and Lil Wayne's "A Milli". Some vocals in the chorus sample Surf Club's "I Can't Miss".

The song received mixed to positive reviews from critics. newmusicreviews said: "The beat is kinda iffy at some points, and the moves from R&B to Hip-Hop seem a little forced, but for the most part the track is decent. 7/10".

Burmy from DjBooth.net speaks that "While Gucci Mane‘s guest verse (no, this is not some late April Fools’ joke) might seem unnecessary to some, Sean Garrett‘s writing and background vocals, together with Bangladesh‘s repetitive, percussion-heavy beat (similar to his work on A Milli and Diva) add up to what could be one of the most widely-spun singles of spring/summer ‘09!".

Various unofficial remixes were made with Mario, Gucci Mane and Sean Garrett still included: one with Bow Wow, another with Nicki Minaj and the last featuring Rick Ross and Young Breed.

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Wikipedia