The bishops of the Roman Catholic diocese of Schwerin (German: Bistum Schwerin), a suffragan of the Metropolitan Archdiocese of Bremen, were simultaneously secular (political) rulers of princely rank (prince-bishop) in the Prince-Bishopric of Schwerin (German: Hochstift Schwerin; established 1180 and secularised in 1648), an imperially immediate state of the Holy Roman Empire. Schwerin was the seat of the chapter, Schwerin Cathedral and residence of the bishops until 1239. In 1180 a prince-episcopal residence was established in Bützow, which became the main residence in 1239.
Not all incumbents of the Schwerin See were imperially invested princely power as Prince-Bishops and not all were papally confirmed as bishops. In 1180 part of the Schwerin diocesan territory were disentangled from the Duchy of Saxony and became an own territory of imperial immediacy called Prince-Bishopric of Schwerin, a vassal of the Holy Roman Empire. The prince-bishopric was an elective monarchy, with the monarch being the respective bishop usually elected by the Cathedral chapter, and confirmed by the Holy See, or exceptionally only appointed by the Holy See. Papally confirmed bishops were then invested by the emperor with the princely regalia, thus the title prince-bishop. However, sometimes the respective incumbent of the see never gained a papal confirmation, but was still invested the princely regalia. Also the opposite occurred with a papally confirmed bishop, never invested as prince. A number of incumbents, elected by the chapter, neither achieved papal confirmation nor imperial investiture, but as a matter of fact nevertheless de facto held the princely power. From 1532 to 1648 all incumbents were Lutherans.