Bis-GMA

Bis-GMA (bisphenol A-glycidyl methacrylate) is a resin commonly used in dental sealants.

Bis-GMA was incorporated into composite dental resins in the 1960s by Rafael Bowen.

Concerns have been raised about the potential for bis-GMA to break down into or be contaminated with the related compound bisphenol A. However, no negative health effects of bis-GMA use in dental resins have been found.

Salivary esterases can slowly degrade bis-GMA-based sealants, forming Bis-HPPP.

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