Biological psychopathology

Biological psychopathology is the study of the biological basis of mental illness. It attempts to elucidate the genetic and neurological etiology behind psychological disorders, including schizophrenia, mood disorders, and anxiety disorders.

Although it interacts with clinical psychology, it is a specialized subset that usually takes place in an experimental context. It is known by several alternative names, including clinical neuroscience and experimental psychopathology.

It is an interdisciplinary approach that comes from sciences such as neuroscience, psychopharmacology, biochemistry, genetics, and physiology, in order to examine the biological basis of behavior and specifically psychopathology. Biological psychopathology and other approaches relating to mental illness are not mutually exclusive, but many basically attempt to deal with the illness through different levels of explanation. Due to the focus on the biological processes of the nervous system, however, biological psychopathology has been particularly important in developing and prescribing drug based treatments for mental disorders. In practice, typically both medication and psychological therapy are used in synchronization to treat mental illness.

Biological psychopathology is specifically offered as a specialty in the PhD program at the University of Minnesota, in its high ranked psychology department.

Biological psychopathology is a field that focuses mostly on the research and understanding the biological basis of major mental disorders such as bipolar and unipolar affective disorder, schizophrenia and Alzheimer's disease. Much of the understanding thus far has come from neuroimaging techniques such as radiotracer positron emission tomography(PET), and functional magnetic resonance imaging (fMRI) scans, as well as genetic studies. Together, neuroimaging with multimodal PET/fMRI, and pharmacological investigations are revealing how the differences in behaviorally-relevant brain activations can arise from underlying variations in certain brain signaling pathways. Understanding the detailed interplay between neurotransmitters and the psychiatric drugs that affect them are key to the research within this field. Significant research includes investigations relevant to biological bases such as biochemical, genetic, physiological, neurological, and anatomical fields. In a clinical viewpoint, the etiology of these diseases takes into account various therapies, diet, drugs, potential environmental contaminants, exercise, and adverse effects of life stressors, all of which can cause noticeable biochemical changes.

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