Bay K8644

Bay K8644

Names
IUPAC name Methyl 2,6-dimethyl-5-nitro-4-[2-(trifluoromethyl)phenyl]-1,4-dihydropyridine-3-carboxylate
Identifiers
CAS Number	71145-03-4 Y
3D model (JSmol)	Interactive image
ChEBI	CHEBI:34555 N
ChemSpider	2213 N
ECHA InfoCard	100.163.930
IUPHAR/BPS	2511
PubChem CID	2303
InChI InChI=1S/C16H15F3N2O4/c1-8-12(15(22)25-3)13(14(21(23)24)9(2)20-8)10-6-4-5-7-11(10)16(17,18)19/h4-7,13,20H,1-3H3 N Key: ZFLWDHHVRRZMEI-UHFFFAOYSA-N N InChI=1/C16H15F3N2O4/c1-8-12(15(22)25-3)13(14(21(23)24)9(2)20-8)10-6-4-5-7-11(10)16(17,18)19/h4-7,13,20H,1-3H3 Key: ZFLWDHHVRRZMEI-UHFFFAOYAV
SMILES CC1=C(C(C(=C(N1)C)[N+](=O)[O-])C2=CC=CC=C2C(F)(F)F)C(=O)OC
Properties
Chemical formula	C16H15F3N2O4
Molar mass	356.30 g·mol−1
Solubility in water	Insoluble
Solubility in other solvents	DMSO: 184 mg/mL; methanol and ethanol: 63 mg/mL
Hazards
EU classification (DSD) (outdated)	Xi
R-phrases (outdated)	R36/38
S-phrases (outdated)	S26 S36
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N  (what is YN ?)
Infobox references

Bay K8644 is a chemical compound that functions as a calcium channel agonist. Bay K8644 is used primarily as a biochemical research tool for this effect. It is a structural analog of nifedipine with positive inotropic activity, and as an aromatic it is highly lipid soluble.

Bay K8644 targets Voltage-sensitive dihydropyridine (DHP) Calcium Channels (L-Type). It is the first positive inotropic agent shown to act specifically and directly on calcium channels.