"Azati Prime" is the eighteenth episode of the third season of the American science fiction television series Star Trek: Enterprise, the 70th overall. The episode was written by Manny Coto from a story developed by Coto, Rick Berman and Brannon Braga. It was directed by Allan Kroeker, his second of the season. The episode featured several guest actors, including those playing members of the Xindi Council, as well as Matt Winston who reprised his role of Temporal Agent Daniels for the second time this season.

Set in the 22nd century, the series follows the adventures of the first Starfleet starship Enterprise, registration NX-01. Season three of Enterprise features an ongoing story following an attack on Earth by previously unknown aliens called the Xindi. In this episode, the crew track a Xindi superweapon down to a planet and Captain Jonathan Archer (Scott Bakula) seeks to destroy the weapon in a suicide attack. He is captured, and the Enterprise is seriously damaged after an attack by four Xindi vessels.

The USS Enterprise-J appeared in this episode, based on designs by Doug Drexler. The ship was from 400 years in the future from the timeframe that the series is set in, and the bridge set was created mostly using green screen. John Eaves also created several designs of aquatic Xindi vessels for this episode. "Azati Prime" received Nielsen ratings of 2.6/4 percent. Critical reaction was mostly positive, with praise directed at the pacing of the episode and the plotting of the overall arc.

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