Ayahuasca

Ayahuasca (UK /ˌaɪjəˈwæskə/; US /ˌaɪjəˈwɑːskə/), and its male counterpart yagé (/jɑːˈheɪ/ or /jæˈheɪ/) or iowaska, is an entheogenic brew made out of Banisteriopsis caapi vine and the Psychotria viridis leaf. The brew is used as a traditional spiritual medicine in ceremonies among the Indigenous peoples of Amazonia.

...
Wikipedia