Asoprisnil

Asoprisnil
Clinical data

ATC code	None
Identifiers
IUPAC name (8S,11R,13S,14S,17S)-11-[4-[(E)-hydroxyiminomethyl]phenyl]-17-methoxy-17-(methoxymethyl)-13-methyl-1,2,6,7,8,11,12,14,15,16-decahydrocyclopenta[a]phenanthren-3-one
CAS Number	199396-76-4^N
PubChem CID	9577221
IUPHAR/BPS	2883
ChemSpider	7851660^Y
UNII	72W09924WP
KEGG	D02996^Y
ChEMBL	CHEMBL267431^Y
Chemical and physical data
Formula	C₂₈H₃₅NO₄
Molar mass	449.582 g/mol
3D model (JSmol)	Interactive image
SMILES O=C5\C=C4/C(=C3/[C@@H](c1ccc(\C=N\O)cc1)C[C@]2([C@@H](CC[C@@]2(OC)COC)[C@@H]3CC4)C)CC5
InChI InChI=1S/C28H35NO4/c1-27-15-24(19-6-4-18(5-7-19)16-29-31)26-22-11-9-21(30)14-20(22)8-10-23(26)25(27)12-13-28(27,33-3)17-32-2/h4-7,14,16,23-25,31H,8-13,15,17H2,1-3H3/b29-16+/t23-,24+,25-,27-,28+/m0/s1^Y Key:GJMNAFGEUJBOCE-MEQIQULJSA-N^Y
^NY (what is this?)

Asoprisnil (INN) (developmental code name J-867) is a synthetic, steroidal selective progesterone receptor modulator (SPRM) which was under development by Schering and TAP Pharmaceutical Products for the treatment of uterine fibroids. In 2005, phase III clinical trials were discontinued due to endometrial changes in patients.

...
Wikipedia

...